Chewable Tablet
Products Forms
Liposomal Chewable Tablet
| Products Name | Mol. Formula | Mol. Weight | Standard Salt |
|---|---|---|---|
| Fe4(P2O7)3 | 745.21 g/mol | Ferric Pyrophosphate | |
| C6H8O6 | 176.12 g/mol | Ascorbic Acid |
Liposomal chewable tablet bridge advanced nanoscale drug delivery with the convenience of traditional chewable formats. By embedding active pharmaceutical ingredients (APIs) within a protective phospholipid bilayer, this format shields sensitive compounds from harsh gastric acids, bypasses first-pass liver metabolism, and optimizes cellular bioavailability.
- Enhanced Bioavailability Potential
Phospholipid-based delivery systems can improve the solubilization, dispersion, protection, and membrane interaction of selected active ingredients, potentially supporting improved absorption. - Protection of Sensitive Actives
Liposomal encapsulation can provide a protective microenvironment for ingredients susceptible to oxidation, degradation, or unfavourable gastrointestinal conditions
Key Formulation & Technical Considerations
- Taste Masking & Palatability: Because chewable tablets expose the API directly to buccal taste receptors, formulators utilize high-intensity sweeteners, bitterness blockers, and masking agents to neutralize active ingredient bitterness. Advanced coating techniques can further isolate bitter cores.
- Better Delivery of Poorly Soluble Ingredients
The technology is particularly attractive for selected lipophilic or poorly water-soluble vitamins, antioxidants, botanical actives, and nutraceutical ingredients. - Mouthfeel & Hardness: Tablets must break down smoothly without a chalky or gritty texture, requiring finely milled API and excipient particle sizes. To remain comfortable for chewing, tablet hardness should ideally stay below 12 kiloponds (kp).
- Mechanical Resilience: To counter the increased friability and dust common with soft tablets during shipping and handling, highly compressible fillers and binders are required.
- Disintegration & Bioavailability: Meeting FDA standards for immediate-release profiles, these tablets are engineered to disintegrate efficiently in saliva, ensuring proper gastrointestinal release and high systemic absorption.
- Premium Product Differentiation
Liposomal tablets allow manufacturers to move beyond conventional supplementation and create technology-driven, premium oral products with a distinctive market proposition.